November 2024

We welcome to our group Amr Elbatrawy (B.S. from Rutgers University), Dylan Miller (B.S. from Northeastern University) and Ke Zheng (B.S. from Imperial College of London).

August 2024

Our paper “Co-Delivery of Valsartan and Metformin from a Thermosensitive Hydrogel-Nanoparticle System Promotes Collagen Production in Proliferating and Senescent Primary Human Dermal Fibroblasts” is published in Biomacromolecules. Congratulations to Paul, Siwei and Aditya, and thanks to our collaborators Profs. Abadir and Walston!

Our collaborative paper “Supramolecular Assembly of Polycation/mRNA Nanoparticles and In Vivo Monocyte Programming” is published in The Proceedings of the National Academy of Sciences (PNAS). Congratulations to all authors and thanks to Dr. Hu and Prof. Mao for this collaboration!

Our paper “Local, Sustained, and Targeted Co-Delivery of MEK Inhibitor and Doxorubicin Inhibits Tumor Progression in E-Cadherin-Positive Breast Cancer” is published in Pharmaceutics. Congratulations to Paul, Aditya, Nanlan, Zack and all co-authors, and thanks to our collaborators Prof. Vo and Prof. Wirtz (co-PI)!

Our collaborative paper “Single-Particle Spectroscopic Chromatography Reveals Heterogeneous RNA Loading and Size Correlations in Lipid Nanoparticles” is published in ACS Nano. Congratulations to all authors and thanks to Dr. Hu and Profs. Mao and Wang for this collaboration!

Our paper “Enantioselective catalysts based on metal-organic framework-supported nucleotides” is published in Microporous and Mesoporous Materials. Congratulations to Danyu and thanks to all our collaborators and Prof. Tsapatsis (co-PI)!

Our paper “Supramolecular Assembly of Single-Tail ssDNA-Amphiphiles Through π–π Interactions” is published in Bioconjugate Chemistry and is featured on a supplementary cover. Congratulations to Huihui, Danyu and Zack and thanks to our collaborator Prof. Tsapatsis!

Zack is a recipient of the 2023 Siebel Scholars award. The Siebel Scholars program annually recognizes the most talented students at the world’s leading graduate schools of business, computer science, bioengineering, & energy science. Zack is one of 5 recipients from JHU. Congratulations Zack!

Our collaborative paper “Payload Distribution and Capacity of mRNA Lipid Nanoparticles” is published in Nature Communications. Congratulations to all authors and thanks to Dr. Hu and Profs. Wang and Mao (PIs) for this collaboration!

Our paper “A localized enantioselective catalytic site on short DNA sequences and their amphiphiles” is published in JACS Au and is featured on a supplementary cover. Congratulations to Danyu, Jun and Huihui and thanks to Prof. Tsapatsis (co-PI) and our collaborators Dr. Pantatosaki and Prof. Papadopoulos!

Our paper “ssDNA nanotubes for selective targeting of glioblastoma and delivery of doxorubicin for enhanced survival” is published in Science Advances. Congratulations to Mike, Zack, Huihui and Lucy and thanks to all our collaborators!

Our paper “Targeted Liposomes Encapsulating miR-603 Complexes Enhance Radiation Sensitivity of Patient-Derived Glioblastoma Stem-Like Cells” has been accepted for publication to Pharmaceutics. Congratulations to Ahmed and Zack and thanks to our collaborator Prof. Chen and his group members Dr. Xu and Dr. Ma!

Jun and Danyu’s paper “A Localized Enantioselective Catalytic Site on Short DNA Sequences and their Amphiphiles” has been posted on ChemRxiv!

Our paper “Thermosensitive and Biodegradable Hydrogel Encapsulating Targeted Nanoparticles for the Sustained Co-Delivery of Gemcitabine and Paclitaxel to Pancreatic Cancer Cells” was published in the International Journal of Pharmaceutics. Congratulations to Ahmed and thanks to our collaborators Dr. Kambhampati, Prof. Hsia and Prof. Kannan!

Our paper “Effect of an alkyl spacer on the morphology and internalization of MUC1 aptamer‐naphthalimide amphiphiles for targeting and imaging triple negative breast cancer cells” was published in Bioengineering & Translational Medicine. Congratulations to our group members Huihui, Zack, Ahmed, Jun, and thanks to our collaborators Gabriella and Prof. Wirtz!

Our paper entitled “Design of an Aptamer-Amphiphile for the Detection of β-Lactoglobulin on a Liquid Crystal Interface” was featured on a cover of Bioconjugate Chemistry’s November 20, 2019 issue. Congratulations Ana, Huihui and Ahmed!

Huihui’s paper entitled “ssDNA-Amphiphile Architecture Used to Control Dimensions of DNA Nanotubes” has been accepted for publication in Nanoscale. Congratulations Huihui!